CloudLinux and Ksplice

Ksplice works well with CloudLinux kernel, as it provides security updates as well as many bug fixes at run time, without the need to reboot the server. As the result you can significantly decrease the number of times you would need to reboot your servers.

Most of the new features are not included in Ksplice updates, and if you need those features, you would need to install a new kernel and reboot the server.